https://chaudhurilab.org/work daily 0.75 2018-08-30 https://images.squarespace-cdn.com/content/v1/5310cef7e4b08602cbfa36bf/1412380988400-7DYABALOM24UK4TSXH5L/image-asset.jpeg Work - COMMERCIAL Add a description of your services here. Cras mattis consectetur purus sit amet fermentum. Justo odio, dapibus ac facilisis. Cum sociis natoque penatibus et magnis dolor sit amet. https://images.squarespace-cdn.com/content/v1/5310cef7e4b08602cbfa36bf/1412380936909-3NDYSVN9D7FZDQHHCO0P/image-asset.jpeg Work - RESIDENTIAL Add a description of your services here. Cum sociis natoque penatibus et magnis dolor sit amet. Natoque penatibus et. Cras justo odio, dapibus ac facilisis in, egestas eget quam. https://images.squarespace-cdn.com/content/v1/5310cef7e4b08602cbfa36bf/1412381139286-DM6BAWCRHNKPBLGZ3QER/Lima01.jpg Work - HOSPITALITY Add a description of your services here. Penatibus et magnis natoque penatibus. Vivamus sagittis lacus vel penatibus augue laoreet rutrum faucibus dolor auctor. https://images.squarespace-cdn.com/content/v1/5310cef7e4b08602cbfa36bf/1395951531371-UHVVQPY7DU2MY6Z73FW2/hayden-header.jpg Work https://chaudhurilab.org/home-1 daily 1.0 2024-09-16 https://images.squarespace-cdn.com/content/v1/5d23a76493c32d00014965d8/1562778560139-A3KHWEK0RFCAKVBN1RII/robina-weermeijer-qIK_fc-4fmw-unsplash.jpg Home https://chaudhurilab.org/research daily 0.75 2019-07-10 https://images.squarespace-cdn.com/content/v1/5d23a76493c32d00014965d8/1562793528023-6PCPX9X75M0VI6GLJY7G/Fig+1+mito+cardiomyopathy+figure.jpg Research In cardiomyopathies triggered by OXPHOS dysfunction, we find increased influx of mitochondrial calcium through the mitochondrial calcium uniporter (green), and diminished efflux through the sodium-calcium exchanger (purple). This leads to enhanced calcium levels in the mitochondrial matrix, potentially both boosting ATP synthesis via a compensatory mechanism, but also leading to mitochondrial dysfunction after excessive accumulation. Figure taken from Sommakia et. al. J Mol Cell Cardiol 2017 https://images.squarespace-cdn.com/content/v1/5d23a76493c32d00014965d8/1562795663633-8P9XXHGACFQ7YK0CKCQG/Mitoplast+image+with+caption.jpg Research Far left, Brightfield image of a mitoplast, with one lobe bounded only by the mitochondrial inner membrane (IMM, white arrow) and one lobe also bounded by the outer membrane (OMM, black arrow). Matrix-targeted mCherry (middle left). GFP-tagged mitofusin-1 (an outer membrane GTPase, middle right). Far right: merged image. 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